Substrate specificity and rational design of peptidomimetic inhibitors for SARS coronavirus main protease.
Identifieur interne : 001563 ( Main/Exploration ); précédent : 001562; suivant : 001564Substrate specificity and rational design of peptidomimetic inhibitors for SARS coronavirus main protease.
Auteurs : K B Wong [Hong Kong] ; D C C. Wan [Hong Kong] ; H F Chow [Hong Kong]Source :
- Hong Kong medical journal = Xianggang yi xue za zhi [ 1024-2708 ] ; 2014.
Descripteurs français
- KwdFr :
- Acides aminés, Concentration inhibitrice 50, Conception de médicament, Cysteine endopeptidases, Inhibiteurs de protéases (synthèse chimique), Oligopeptides (synthèse chimique), Peptidomimétiques (synthèse chimique), Protéines virales (antagonistes et inhibiteurs), Spécificité du substrat, Structure moléculaire, Virus du SRAS (enzymologie).
- MESH :
- antagonistes et inhibiteurs : Protéines virales.
- enzymologie : Virus du SRAS.
- synthèse chimique : Inhibiteurs de protéases, Oligopeptides, Peptidomimétiques.
- Acides aminés, Concentration inhibitrice 50, Conception de médicament, Cysteine endopeptidases, Spécificité du substrat, Structure moléculaire.
English descriptors
- KwdEn :
- Amino Acids, Cysteine Endopeptidases, Drug Design, Inhibitory Concentration 50, Molecular Structure, Oligopeptides (chemical synthesis), Peptidomimetics (chemical synthesis), Protease Inhibitors (chemical synthesis), SARS Virus (enzymology), Substrate Specificity, Viral Proteins (antagonists & inhibitors).
- MESH :
- chemical , antagonists & inhibitors : Viral Proteins.
- chemical , chemical synthesis : Oligopeptides, Peptidomimetics, Protease Inhibitors.
- chemical : Amino Acids, Cysteine Endopeptidases.
- enzymology : SARS Virus.
- Drug Design, Inhibitory Concentration 50, Molecular Structure, Substrate Specificity.
PubMed: 25224113
Affiliations:
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Le document en format XML
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